Connect with us

Health

SARS-CoV-2 is activated for fusion by a broad range of proteases, finds study – News-Medical.Net

A team of researchers from the University of Virginia, USA, used single-virus fusion experiments with exogenously controlled proteases to investigate the mechanism…

Published

on

Article feature image
ADVERTISEMENT

It is well known that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds with the angiotensin-converting enzyme 2 (ACE2) receptor on the host cell surface. This process facilitates host-virus membrane fusion, with cell entry achieved by host proteases.
The particular host protease utilized varies amongst betacoronaviruses, though SARS-CoV-2 appears to use cathepsins primarily, usually found in the late endosome, suggesting that SARS-CoV-2 enters the cell by the endocytotic pathway….

Click here to view the original article.

Continue Reading
Advertisement

You might also like ...

Article feature image
Scientists demonstrate promising new approach for treating cystic fibrosis – EurekAlert
Article feature image
Study finds Moderna vaccine reduces COVID infection after just eight days – The New Daily